Anti-inflammatory agent 50
Anti-inflammatory agent 50 (compound a1) is a Fusidic acid derivative with anti-inflammatory effects. Anti-inflammatory agent 50 inhibits inflammatory factor NO, IL-6 and TNF-α. Anti-inflammatory agent 50 alleviates acute lung injury by regulating inflammatory mediators and suppressing the MAPK, NF-κB and NLRP3 inflammasome signaling pathways.
For research use only. We do not sell to patients.
- Formula: C40H55N3O6
- Molecular Weight:673.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
In LPS-induced RAW264.7 cells, Anti-inflammatory agent 50 (compound a1) inhibits inflammatory factor NO (IC50 of 3.26 μM), IL-6 (IC50 of 1.85 μM) and TNF-α (IC50 of 3.88 μM). Anti-inflammatory agent 50 markedly inhibits the expression of certain immune-related cytotoxic factors, including COX-2 and inducible nitric-oxide synthase (iNOS)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 673.88
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Formula C40H55N3O6
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SMILES
C/C(C)=C\CC/C(C(OCC1=CN(C2=CC=CC=C2)N=N1)=O)=C3[C@@H](OC(C)=O)C[C@]4(C)[C@@]5(C)CC[C@@]6([H])[C@H](C)[C@H](O)CC[C@]6(C)C5[C@H](O)C[C@@]/34[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-inflammatory agent 50 Related Classifications
HY-155753 Related Classifications
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