6-Chloro-L-tryptophan
Based on 1 Customer Validation
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ.
For research use only. We do not sell to patients.
- Purity: 99.50%
- CAS No.: 33468-35-8
- Formula: C11H11ClN2O2
- Molecular Weight:238.67
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6-Chloro-L-tryptophan (0-500 μM) exhibits no inhibitory effect on D-amino acid oxidase (DAO)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 33468-35-8
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Appearance Solid
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Molecular Weight 238.67
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Formula C11H11ClN2O2
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Color White to gray
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M NaOH : ≥ 100 mg/mL (418.99 mM)
H2O : 50 mg/mL (209.49 mM; ultrasonic and warming and adjust pH to 12 with 1M NaOH and heat to 60°C)
DMSO : 2 mg/mL (8.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Heemstra JR Jr, et al. Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly. J Am Chem Soc. 2008 Oct 29;130(43):14024-5. [Content Brief]
[2]. Iwasaki M, et al. A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity. Biomed Chromatogr. 2016 Mar;30(3):384-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O / 1 M NaOH | 1 mM | 4.1899 mL | 20.9494 mL | 41.8989 mL | 104.7471 mL |
| 5 mM | 0.8380 mL | 4.1899 mL | 8.3798 mL | 20.9494 mL | |
| H2O / 1 M NaOH | 10 mM | 0.4190 mL | 2.0949 mL | 4.1899 mL | 10.4747 mL |
| 15 mM | 0.2793 mL | 1.3966 mL | 2.7933 mL | 6.9831 mL | |
| 20 mM | 0.2095 mL | 1.0475 mL | 2.0949 mL | 5.2374 mL | |
| 25 mM | 0.1676 mL | 0.8380 mL | 1.6760 mL | 4.1899 mL | |
| 30 mM | 0.1397 mL | 0.6983 mL | 1.3966 mL | 3.4916 mL | |
| 40 mM | 0.1047 mL | 0.5237 mL | 1.0475 mL | 2.6187 mL | |
| 50 mM | 0.0838 mL | 0.4190 mL | 0.8380 mL | 2.0949 mL | |
| 60 mM | 0.0698 mL | 0.3492 mL | 0.6983 mL | 1.7458 mL | |
| 80 mM | 0.0524 mL | 0.2619 mL | 0.5237 mL | 1.3093 mL | |
| 100 mM | 0.0419 mL | 0.2095 mL | 0.4190 mL | 1.0475 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
6-Chloro-L-tryptophan Related Classifications
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