PRMT5-MTA-IN-6
PRMT5-MTA-IN-6 (Compound 31) is a selective MTA-cooperative PRMT5 inhibitor. PRMT5-MTA-IN-6 exhibits potent inhibitory activity against PRMT5・MTA (IC50: 6.6 nM). PRMT5-MTA-IN-6 selectively inhibits the growth of MTAP-deleted HCT-116 cells (IC50: 319 nM). PRMT5-MTA-IN-6 can be used in the research of MTAP-deleted tumors.
For research use only. We do not sell to patients.
- Formula: C26H26N6O2
- Molecular Weight:454.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 454.52
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Formula C26H26N6O2
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SMILES
NCC1=NNC(C2=CC=C(C=C21)C3=C4N(CCN4N=C3)CC5=CC(C6CC6)=CC7=C5OCC7)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)