VEGFR-2-IN-66
VEGFR-2-IN-66 (Compound 6) is an orally active VEGFR-2 inhibitor with an IC50 value of 0.509 µM and an IC50 value of 7.48 μM for inhibiting the proliferation of MCF-7 cells. VEGFR-2-IN-66 exerts its anti-cancer activity by arresting the cell cycle, inducing apoptosis, and regulating gene expression, and can be used in the research of the breast cancer field.
For research use only. We do not sell to patients.
- Formula: C20H22N8O3
- Molecular Weight:422.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR2 509 nM (IC50) |
Chemical Information
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Molecular Weight 422.44
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Formula C20H22N8O3
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SMILES
O=C(NC1CCC(NC1=O)=O)CN(CC2)CCN2C3=NC4=CC=CC=C4C5=NN=CN35
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)