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Cat. No.: HY-107773R

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GSK3004774 (Standard)

GSK3004774 (Standard) is the analytical standard of GSK3004774 (HY-107773). This product is intended for research and analytical applications. GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC₅₀ of 7.3, 6.6 and 6.5 for human, mouse and rat CaSR, respectively. GSK3004774 shows an EC₅₀ of 50 nM for human CaSR.

For research use only. We do not sell to patients.

CAS No.: 2138814-32-9
Formula: C₃₂H₄₀N₄O₃
Molecular Weight:528.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GSK3004774 (Standard) Chemical Structure

CAS No.: 2138814-32-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 2138814-32-9
Molecular Weight 528.69
Formula C₃₂H₄₀N₄O₃
SMILES

O=C(NCCCN1CCC(C(O)=O)CC1)C(C=C2)=CC=C2N(CC3)C[C@H]3N[C@H](C)C4=CC=CC5=C4C=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sparks SM, et al. Identification of potent, nonabsorbable agonists of the calcium-sensing receptor for GI-specific administration. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4673-4677. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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