6-O-Caffeoylarbutin
Based on 1 Customer Validation
6-O-Caffeoylarbutin (Robustaside B) possesses antioxidant activity. 6-O-Caffeoylarbutin ameliorates neurological functions and deficits in ischemic mice.
For research use only. We do not sell to patients.
- Purity: 99.47%
- CAS No.: 136172-60-6
- Formula: C21H22O10
- Molecular Weight:434.39
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
In the presence of calcium, similar concentrations of robustaside B decreases the extent
of MPT pore opening in a concentration-dependent manner but in the reverse order[1].
Robustaside B (0.1mM) and para-hydroxyphenol(0.05mM) significantly inhibits mitochondrial lipid peroxidation induced by the Fe2+/ascorbate system by causing a significant decrease (86.4 and 86.7%), respectively, in the amount of TBARS released by the system[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136172-60-6
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Appearance Solid
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Molecular Weight 434.39
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Formula C21H22O10
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Color White to off-white
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SMILES
OC(C=C1/C=C/C(OC[C@H]([C@H]([C@@H]([C@H]2O)O)O)O[C@H]2OC3=CC=C(C=C3)O)=O)=C(C=C1)O
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Synonyms
Robustaside B
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Rahmat A Adisa, et al. Robustaside B and para‑hydroxyphenol: phenolic and antioxidant compounds purified from Cnestis ferruginea D.C induced membrane permeability transition in rat liver mitochondria. Mol Med Rep. 2013 Nov;8(5):1493-8. [Content Brief]
[2]. Shi ZQ, Wen X, Wu XR, et al. 6'-O-caffeoylarbutin of Vaccinium dunalianum alleviated ischemic stroke through the PI3K/AKT/NF-κB pathway. Phytomedicine. 2025;139:156505. [Content Brief]
[3]. Wang Y, Wang Y, Zhao T, et al. 6'-O-caffeoylarbutin attenuates D-galactose-induced brain and liver damage in aging mice via regulating SIRT1/NF-κB pathway. Phytomedicine. 2025;141:156710. [Content Brief]
[4]. Wang YP, Wang YD, Liu YP, et al. 6'-O-Caffeoylarbutin from Que Zui tea ameliorates acetaminophen-induced liver injury via enhancing antioxidant ability and regulating the PI3K signaling pathway. Food Funct. 2022;13(9):5299-5316. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-O-Caffeoylarbutin Related Classifications
HY-N2720 Related Classifications
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