TBK1 degrader-4
TBK1 degrader-4 (Compound 30) is a molecular glue degrader targeting TBK1. TBK1 degrader-4 effectively inhibits cyst growth, alleviates inflammation, and reduces the levels of pro-inflammatory factors such as Ccl2, IFNβ, and IL-6. TBK1 degrader-4 is promising for research of autosomal dominant polycystic kidney disease (ADPKD).
For research use only. We do not sell to patients.
- Formula: C42H52N8O4
- Molecular Weight:732.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 732.91
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Formula C42H52N8O4
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SMILES
O=C(N1CCN(CC2CCN(CC3=CC(NC4=NC=C(C=CN5CCCNC(C6CCC6)=O)C5=N4)=CC=C3)CC2)CC1)/C=C/C(C7=CC=C(OC)C=C7)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)