RP-4029
RP-4029 is a selective, covalent hPolθ inhibitor (IC50s: 0.013 nM for hPolθ; 6.6 nM for mPolθ). RP-4029 can be used in the research of homologous recombination (HR)-deficient cancers.
For research use only. We do not sell to patients.
- Formula: C29H23F6N3O4S
- Molecular Weight:623.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
IC50s: 0.013 nM for hPolθ; 6.6 nM for mPolθ[1]
Chemical Information
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Molecular Weight 623.57
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Formula C29H23F6N3O4S
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SMILES
O=C(N(C1=CC=CC=C1)CC#CCNC(C2=C(NS(C=C)(=O)=O)C=CC=C2)=O)CC3=CC=C(C(F)(F)F)C=C3C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)