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EGFR-IN-144

EGFR-IN-144 (Compound 4B) exhibits inhibitory activities against EGFR (IC50=0.639 µg/mL) and tubulin polymerization (IC50=7.339 µg/mL). EGFR-IN-144 exhibits cytotoxicity in multiple cancer cell with GI50 of nanomolare levels. EGFR-IN-144 downregulates the expressions of mTOR, TNF-α, and IL-6, arrests the cell cycle at G1/S phase, and induces apoptosis.

For research use only. We do not sell to patients.

  • Formula: C20H17Cl2N3O3
  • Molecular Weight:418.27
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR-IN-144 Chemical Structure
    EGFR-IN-144 Chemical Structure
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All EGFR Isoforms

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All Interleukin Related Isoforms

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All TNF Receptor Isoforms

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100 mg

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  • EGFR-IN-144 Chemical Structure
    EGFR-IN-144 Chemical Structure
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  • EGFR-IN-144