6-Methoxytricin
Based on 1 Customer Validation
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC50 values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.42%
- No. CAS: 76015-42-4
- Fòrmula: C18H16O8
- Peso molecular:360.31
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-50289
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HY-16500
TolrestatAldose Reductase Inhibitor -
HY-16500R
Tolrestat (Standard)Aldose Reductase Inhibitor -
HY-16255
ImirestatAldose Reductase Inhibitor -
HY-16433
RisarestatAldose Reductase Inhibitor -
HY-66009
EpalrestatAldose Reductase Inhibitor -
HY-50289R
Sorbinil (Standard)Aldose Reductase Inhibitor -
HY-16255R
Imirestat (Standard)Aldose Reductase Inhibitor -
HY-106697
PonalrestatAldose Reductase Inhibitor -
HY-N4089
Quercetin 3-gentiobiosideAromatase Inhibitor -
HY-66009R
Epalrestat (Standard)Aldose Reductase Inhibitor -
HY-18967
CaficrestatAldose Reductase Inhibitor
Actividad biológica
Descripciòn
IC50 & Target
IC50: 30.29 μM (AR); 134.88 μM (AGE) (6-Methoxytricin)[1]
Chemical Information
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No. CAS 76015-42-4
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Appearance Solid
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Peso molecular 360.31
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Fòrmula C18H16O8
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Color Off-white to light yellow
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SMILES
O=C1C=C(C2=CC(OC)=C(O)C(OC)=C2)OC3=C1C(O)=C(OC)C(O)=C3
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 100 mg/mL (277.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7754 mL | 13.8769 mL | 27.7539 mL | 69.3847 mL |
| 5 mM | 0.5551 mL | 2.7754 mL | 5.5508 mL | 13.8769 mL | |
| 10 mM | 0.2775 mL | 1.3877 mL | 2.7754 mL | 6.9385 mL | |
| 15 mM | 0.1850 mL | 0.9251 mL | 1.8503 mL | 4.6256 mL | |
| 20 mM | 0.1388 mL | 0.6938 mL | 1.3877 mL | 3.4692 mL | |
| 25 mM | 0.1110 mL | 0.5551 mL | 1.1102 mL | 2.7754 mL | |
| 30 mM | 0.0925 mL | 0.4626 mL | 0.9251 mL | 2.3128 mL | |
| 40 mM | 0.0694 mL | 0.3469 mL | 0.6938 mL | 1.7346 mL | |
| 50 mM | 0.0555 mL | 0.2775 mL | 0.5551 mL | 1.3877 mL | |
| 60 mM | 0.0463 mL | 0.2313 mL | 0.4626 mL | 1.1564 mL | |
| 80 mM | 0.0347 mL | 0.1735 mL | 0.3469 mL | 0.8673 mL | |
| 100 mM | 0.0278 mL | 0.1388 mL | 0.2775 mL | 0.6938 mL |
6-Methoxytricin Related Classifications
HY-N6883 Related Classifications
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