Patrinoside aglucone
Patrinoside aglucone (Compound 8) is an iridoid glucoside that can be isolated from the Valeriana tuberosa. Patrinoside aglucone has potent anticancer activity with G2/M phase tumor cell cycle arrest and apoptosis induction. Patrinoside aglucone also significantly inhibits the proliferation of cancer stem cells (such as MDA-MB-231 and U-251MG cells). Patrinoside aglucone has great anti-inflammatory activity by inhibiting NO release (IC50: 43.44 μM) and significantly reduces the level of TNF-α, IL-1β, IL-6, PGE2 and COX-2.
For research use only. We do not sell to patients.
- CAS No.: 76319-15-8
- Formula: C15H24O6
- Molecular Weight:300.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IL-6 |
IL-1β |
COX-2 |
Chemical Information
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CAS No. 76319-15-8
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Molecular Weight 300.35
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Formula C15H24O6
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SMILES
CC(C)CC(O[C@H]1[C@@]2([H])[C@@](C[C@@H]([C@@H]2CO)O)([H])C(CO)=CO1)=O
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Synonyms
Patrinoside aglycone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Çelik C, et al. Exploring the anti-inflammatory and cytotoxic effects of Valeriana tuberosa L. constituents: Integrating in vitro and in silico studies. Fitoterapia. 2025 Jul;184:106604. [Content Brief]
[2]. Yoshikawa H, et al. Anti-Proliferative Effects of Iridoids from Valeriana fauriei on Cancer Stem Cells. Int J Mol Sci. 2022 Nov 17;23(22):14206. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Patrinoside aglucone Related Classifications
HY-160121 Related Classifications
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