12R-LOX-IN-1
12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research.
For research use only. We do not sell to patients.
- CAS No.: 857758-13-5
- Formula: C15H11NO2
- Molecular Weight:237.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 857758-13-5
-
Molecular Weight 237.25
-
Formula C15H11NO2
-
SMILES
OC1=CC=C(N=C(C2=CC=CC=C2O)C=C3)C3=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)