12R-LOX-IN-1

12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research.

For research use only. We do not sell to patients.

  • CAS No.: 857758-13-5
  • Formula: C15H11NO2
  • Molecular Weight:237.25
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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