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Trehalose 6-behenate 

Cat. No.: HY-101871
Handling Instructions

Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.

For research use only. We do not sell to patients.

Trehalose 6-behenate Chemical Structure

Trehalose 6-behenate Chemical Structure

CAS No. : 66755-19-9

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Description

Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.

IC50 & Target

Trehalose 6-behenate (TDB) exerts its effect through binding to the macrophage-inducible C-type lectin Mincle, a pathogen recognition receptor (PRR) that recognises pathogen-associated molecular patterns (PAMPs). The potential of Th1/Th17 skewing adjuvants in vaccine development provides a very real incentive for better definition of the structural motifs required for Mincle binding. Mincle is highly conserved between mice and humans, with 85 % protein similarity. In addition to being a receptor for TDMs, Trehalose 6-behenate (TDB), and the spliceosome-associated protein (SAP)130 (which activates Mincle at a binding site different to that involved in carbohydrate recognition), Mincle is also a receptor for Candida albicans, Malassezia, and Fonsecaea pedrosoi[1].

Molecular Weight

664.86

Formula

C₃₄H₆₄O₁₂

CAS No.

66755-19-9

SMILES
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Trehalose 6-behenate
Cat. No.:
HY-101871
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