2. Immunology/Inflammation
  3. IRAK
  4. PROTAC IRAK4 degrader-8

PROTAC IRAK4 degrader-8 (compound 2) is a PROTAC targeting to IRAK4 (IC50=15.5 nM).

For research use only. We do not sell to patients.

PROTAC IRAK4 degrader-8 Chemical Structure

PROTAC IRAK4 degrader-8 Chemical Structure

CAS No. : 2911615-06-8

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PROTAC IRAK4 degrader-8 Related Antibodies

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Description

PROTAC IRAK4 degrader-8 (compound 2) is a PROTAC targeting to IRAK4 (IC50=15.5 nM)[1].

IC50 & Target

IRAK4
Molecular Weight

874.38

Formula

C43H50ClF2N11O5
CAS No.
SMILES

O=C(C(C=C1)=CC(N(CCC2=O)C(N2)=O)=C1Cl)N3CCC(CCN4C[C@H]5CC[C@H](N(N=C6C(F)F)C=C6NC(C7=C(N=C(N8[C@](CO9)([H])C[C@]9([H])C8)C=C%10)N%10N=C7)=O)CC5)(CC4)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC IRAK4 degrader-8 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC IRAK4 degrader-82911615-06-8IRAKInterleukin-1 receptor associated kinaseIL-1R associated kinasePROTACInhibitorinhibitorinhibit

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PROTAC IRAK4 degrader-8
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HY-153673
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