1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. 6-Hydroxy-DOPA

6-Hydroxy-DOPA 

Cat. No.: HY-110286
Handling Instructions

6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer.

For research use only. We do not sell to patients.

6-Hydroxy-DOPA Chemical Structure

6-Hydroxy-DOPA Chemical Structure

CAS No. : 21373-30-8

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Description

6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].

IC50 & Target

RAD52[1]

In Vitro

6-Hydroxy-DOPA (0~20 μM; U20S cells) selectively inhibits RAD52-mediated recombination. 6-Hydroxy-DOPA (0~10 μM; HEK293T cells) decreases the number of eGFP-RAD52 foci in a dose-dependent manner. 6-Hydroxy-DOPA (5~75 μM; HCC1937 cells) selectively reduces the viability of the BRCA1-deficient triple-negative breast cancer cell line HCC1937[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

213.19

Formula

C₉H₁₁NO₅

CAS No.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
6-Hydroxy-DOPA
Cat. No.:
HY-110286
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