2. Search Result
Search Result
Results for "

pyrazolidinone； bacterial

" in MedChemExpress (MCE) Product Catalog:

2235

Inhibitors & Agonists

12

Screening Libraries

47

Fluorescent Dyes

86

Biochemical Assay Reagents

215

Peptides

20

MCE Kits

7

Inhibitory Antibodies

554

Natural
Products

174

Isotope-Labeled Compounds

9

Click Chemistry

19

Oligonucleotides

2

GMP Molecules

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131045
    HADA hydrochloride
    5+ Cited Publications

    HCC-Amino-D-alanine hydrochloride

    		 Bacterial Infection
    HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
    HADA hydrochloride
  • HY-13234
    Rifaximin
    5+ Cited Publications

    		 Bacterial Antibiotic DNA/RNA Synthesis Infection Cancer
    Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
    Rifaximin
  • HY-P1004
    Luciferase (bacterial)

    		Biochemical Assay Reagents Cancer
    Luciferase (bacterial) catalyzes the oxidation of a long-chain aldehyde and reduced flavin mononucleotide. Luciferase (bacterial) protection against oxidative stress for bacterial luminescence .
    Luciferase (bacterial)
  • HY-B0915
    Orbifloxacin
    1 Publications Verification

    CP-104354

    		 Bacterial Antibiotic Infection
    Orbifloxacin is an orally administrable Antibiotic. Orbifloxacin disrupts the replication and proliferation of Bacterial DNA, inhibits bacterial growth and exerts bactericidal activity. Orbifloxacin inhibits the growth of canine-derived E. coli and Pseudomonas aeruginosa isolates. Orbifloxacin is used in research related to bacterial infections .
    Orbifloxacin
  • HY-D1056B3
    Lipopolysaccharides, from Klebsiella pneumoniae

    LPS, from bacterial (Klebsiella pneumoniae)

    		 Toll-like Receptor (TLR) Inflammation/Immunology
    Lipopolysaccharides, from Klebsiella pneumoniae (LPS, from bacterial (Klebsiella pneumoniae)) are lipopolysaccharide endotoxins and TLR4 activators derived from Klebsiella pneumoniae, and are classified as S-type LPS. Lipopolysaccharides, from Klebsiella pneumoniae exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Klebsiella pneumoniae may participate in bacterial immune evasion by inhibiting complement-mediated killing and suppressing the host's secretion of antimicrobial peptides, thereby allowing the bacteria to escape immune defenses. Lipopolysaccharides, from Klebsiella pneumoniae possess high viscosity and resistance to serum-mediated killing, which may lead to sepsis. Lipopolysaccharides, from Klebsiella pneumoniae can be used to construct Acute Lung Injury Model .
    It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.
    Lipopolysaccharides, from Klebsiella pneumoniae
  • HY-16908A
    Lefamulin acetate
    4 Publications Verification

    BC-3781 acetate

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin acetate
  • HY-P2968
    Bacterial α-Amylase

    		Amylases Others
    Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies .
    Bacterial α-Amylase
  • HY-P1883A
    Bacterial Sortase Substrate III, Abz/DNP TFA

    		Fluorescent Dye Infection
    Bacterial Sortase Substrate III, Abz/DNP TFA is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP TFA undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
    Bacterial Sortase Substrate III, Abz/DNP TFA
  • HY-N13356
    L-gamma-Glutamyl-L-threonine

    gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr

    		 Bacterial Peptide-Drug Conjugates (PDCs) Drug Metabolite Infection Inflammation/Immunology
    L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
    L-gamma-Glutamyl-L-threonine
  • HY-A0253
    Cefacetrile

    Cephacetrile; Cephacetril

    		 Bacterial Antibiotic Infection
    Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .
    Cefacetrile
  • HY-142127
    Ribostamycin
    1 Publications Verification

    Vistamycin; SF-733

    		 Bacterial Antibiotic PDI Infection
    Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .
    Ribostamycin
  • HY-DY1044
    HADA hydrochloride (solution)

    		Bacterial Infection
    HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation .
    Solvent and concentration: DMSO: 50 mM
    HADA hydrochloride (solution)
  • HY-B1497
    Silver sulfadiazine
    1 Publications Verification

    AgSD

    		 Bacterial DNA/RNA Synthesis Antibiotic Infection
    Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .
    Silver sulfadiazine
  • HY-W011117
    Danofloxacin

    		Bacterial DNA/RNA Synthesis Antibiotic Infection
    Danofloxacin is an orally active quinolone antibiotic. Danofloxacin targets bacterial DNA gyrase and inhibits bacterial DNA replication, transcription and growth. Danofloxacin can be used for various bacterial infections caused by Escherichia coli, Mycoplasma and other pathogens .
    Danofloxacin
  • HY-135532
    Amoxicillin-clavulanate potassium

    		Antibiotic Infection
    Amoxicillin-clavulanate potassium is an antibiotic. Amoxicillin-clavulanate potassium has the potential for the research of various bacterial infection .
    Amoxicillin-clavulanate potassium
  • HY-115249
    Metronidazole acetic acid

    		Bacterial Infection
    Metronidazole acetic acid is a metabolite of Metronidazole (HY-B0318) and exhibits mutagenic activity in bacterial .
    Metronidazole acetic acid
  • HY-N11874
    Staphyloferrin A

    		Bacterial Infection
    Staphyloferrin A is a carboxylate-type siderophore, as well as an iron (III) chelator and a HtsA ligand with high binding affinity for iron (III). Staphyloferrin A can be used in studies of bacterial infections .
    Staphyloferrin A
  • HY-16908
    Lefamulin
    4 Publications Verification

    BC-3781

    		 Bacterial Antibiotic Infection
    Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin has anti-inflammatory activity. Lefamulin can be used in the research of bacterial infections, such as bacterial pneumonia .
    Lefamulin
  • HY-W045071
    N-Hexanoyl-DL-homoserine lactone

    		Bacterial Infection
    N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere .
    N-Hexanoyl-DL-homoserine lactone
  • HY-B1741
    3,6-Diaminoacridine
    3 Publications Verification

    		 Bacterial Fluorescent Dye DNA/RNA Synthesis Infection Cancer
    3,6-Diaminoacridine is a versatile acridine compound. 3,6-Diaminoacridine exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine is an acridine dye and also a DNA intercalator .
    3,6-Diaminoacridine
  • HY-157573
    N-Acetylmuramic acid-azide
    1 Publications Verification

    		 Bacterial Infection
    N-Acetylmuramic acid-azide (Compound 2) is a derivative of N-acetylaminoacetic acid (NAM) in bacterial peptidoglycan. Incorporated into bacterial peptidoglycan during biosynthesis .
    N-Acetylmuramic acid-azide
  • HY-117685
    Cefovecin sodium

    		Antibiotic Bacterial Infection
    Cefovecin sodium is an extended-spectrum semisynthetic cephalosporin and bactericidal agent. Cefovecin sodium exerts potent antibacterial activity against multiple bacterial. Cefovecin sodium can be used for the research of bacterial infection .
    Cefovecin sodium
  • HY-157345
    Nutrient Agar

    		Bacterial Others
    Nutrient Agar is a special agar for bacterial culture. The composition of 1 litre medium is 33 g Nutrient Agar .
    Nutrient Agar
  • HY-136638
    ML328

    		DNA/RNA Synthesis Bacterial Infection
    ML328 is a selective inhibitor of bacterial AddAB and RecBCD helicase-nucleases with IC50 values of 26 and 5.1 μM, respectively. ML328 is a gyrase inhibitor. ML328 strongly inhibits the growth of E. coli in the presence of phage. ML328 can be used for the research of bacterial infection .
    ML328
  • HY-106571
    Cefteram pivoxil

    Ro 19-5248; T-2588

    		 Bacterial Antibiotic Infection
    Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections .
    Cefteram pivoxil
  • HY-111331
    Germicidin B

    		Antibiotic Hexokinase Bacterial Infection
    Germicidin B is an antibiotic with bactericidal activity. Germicidin B inhibits hexokinase II with an IC50 of 25.16 μM. Germicidin B suppresses spore germination in Streptomyces. Germicidin B is applicable to studies on bacterial infections .
    Germicidin B
  • HY-14784
    Bederocin

    REP8839

    		 Bacterial Infection
    Bederocin (REP8839) is a Methionyl-tRNA synthetase inhibitor. Bederocin can be used in research of bacterial infection, including S. aureus and MRSA .
    Bederocin
  • HY-103658
    Myramistin

    Miramistin

    		 Bacterial Infection
    Myramistin (Miramistin) is an antibacterial agent targeting bacterial cell membrane. Myramistin can bind to the negatively charged surface of bacteria through its cationic properties, disrupt the integrity of the bacterial cell membrane, inhibit bacterial metabolism and growth, and induce cell death, thus exerting antibacterial activity .
    Myramistin
  • HY-157372
    Peptone Bacteriological

    		Bacterial Others
    Peptone Bacteriological is used as a medium material to provide nitrogen source and amino acid for bacterial growth .
    Peptone Bacteriological
  • HY-P1883
    Bacterial Sortase Substrate III, Abz/DNP

    		Fluorescent Dye Infection
    Bacterial Sortase Substrate III, Abz/DNP is a fluorescent peptide substrate. Bacterial Sortase Substrate III, Abz/DNP undergoes cleavage catalyzed by Staphylococcus aureus sortase A (SrtAΔN24) and Streptococcus pyogenes sortase A (SrtAΔN81), and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of the cell wall cross-bridge. Cleavage of this substrate can be detected at Ex/Em=320 nm/420 nm .
    Bacterial Sortase Substrate III, Abz/DNP
  • HY-P3326A
    Targeting the bacterial sliding clamp peptide 46 TFA

    		Bacterial Infection
    Targeting the bacterial sliding clamp peptide 46 TFA is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis .
    Targeting the bacterial sliding clamp peptide 46 TFA
  • HY-P10980
    Citrocin

    		DNA/RNA Synthesis Bacterial Infection
    Citrocin is a potent bacterial RNA polymerase (RNAP) inhibitor. Citrocin shows significant inhibitory activity against Escherichia coli RNAP with an MIC range of 16-125 μM. Citrocin specifically binds to and inhibits RNA polymerase to block bacterial transcription and enters cells mainly through inner membrane protein SbmA. Citrocin is promising for research of Gram-negative bacterial infections, such as enterohemorrhagic E. coli .
    Citrocin
  • HY-153518
    LpxC-IN-11

    		Bacterial Infection
    LpxC-IN-11 (Compound 1) is an LpxC inhibitor. LpxC-IN-11 can be used in the research of bacterial infectious diseases .
    LpxC-IN-11
  • HY-139554
    Zifanocycline

    KBP-7072

    		 Antibiotic Bacterial Infection
    Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
    Zifanocycline
  • HY-19581
    Baquiloprim

    		Antibiotic Bacterial Infection
    Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .
    Baquiloprim
  • HY-D1485
    3,3'-Diethylthiacyanine iodide

    		Bacterial Others
    3,3'-Diethylthiacyanine iodide is a cyanine fluorescent dye. 3,3'-Diethylthiacyanine iodide manifestes a pronounced affinity for bacterial cells .
    3,3'-Diethylthiacyanine iodide
  • HY-P3326
    Targeting the bacterial sliding clamp peptide 46

    		Bacterial Infection
    Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
    Targeting the bacterial sliding clamp peptide 46
  • HY-175301
    TH16

    		Bacterial Reactive Oxygen Species (ROS) Infection
    TH16 is an antibacterial agent (MIC=2 μg/mL against methicillin-resistant Staphylococcus aureus, MRSA). TH16 disrupts bacterial cytoplasmic membrane integrity, elevating intracellular reactive oxygen species (ROS) levels to induce bacterial death. TH16 is promising for research of bacterial infection .
    TH16
  • HY-N16419
    Haenamindole

    		Drug Derivative Infection Cancer
    Haenamindole is an alkaloid. Haenamindole is promising for research of bacterial infection and cancers .
    Haenamindole
  • HY-N12498
    Aureonuclemycin

    		Antibiotic Bacterial Infection
    Aureonuclemycin can be isolated from Staphylococcus aureus to obtain its biosynthetic gene cluster. Aureonuclemycin exists in two forms: Type A and Type B. Aureonuclemycin A is a nucleoside antibiotic that is structurally similar to herbicides and contains adenine. Aureonuclemycin B contains 5′-deoxyadenosine and exhibits antibacterial activity. Aureonuclemycin can be used in the research of bacterial leaf blight in rice, citrus canker, and bacterial leaf spot in rice. .
    Aureonuclemycin
  • HY-139424
    SQ609

    		Bacterial Cancer
    SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .
    SQ609
  • HY-135397
    (R)-​Linezolid

    (R)-PNU-100766

    		 Drug Metabolite Infection
    (R)-Linezolid is an impurity of Linezolid (PNU-100766). Linezolid, the first member of the class of oxazolidinone synthetic antibiotic, acts by inhibiting the initiation of bacterial protein synthesis .
    (R)-​Linezolid
  • HY-139982
    OX11

    		Bacterial Infection
    OX11 is a selective inhibitor of S. pneumoniae, P. aeruginosa, and E. coli bacterial strains .
    OX11
  • HY-N3769
    Dipterocarpol

    		Others Infection Inflammation/Immunology
    Dipterocarpol is a dammarane-type triterpenoid. Dipterocarpol is substrate of the bacterial steroid-hydroxylase CYP106A2 .
    Dipterocarpol
  • HY-120658
    (Rac)-LY193239

    		Antibiotic Bacterial Infection
    (Rac)-LY193239 is a racemic modification of LY193239 (HY-120658A). LY193239 is a higher-lactam pyrazolidinone antibacterial agent .
    (Rac)-LY193239
  • HY-NP025
    E.coli Bacterial protein

    EPEC

    		 Bacterial Infection
    E.coli Bacterial protein is a native protein that can be isolated from E.coli .
    E.coli Bacterial protein
  • HY-120583
    (Rac)-LY 255262

    		Bacterial Infection
    (Rac)-LY 255262 is a pyrazolidinone-derivative that has antibacterial activity .
    (Rac)-LY 255262
  • HY-157359
    Bacterial Organophosphorus Medium

    		Biochemical Assay Reagents Others
    Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
    Bacterial Organophosphorus Medium
  • HY-NP016
    Brucella bacterial protein

    		Bacterial Biochemical Assay Reagents Others
    Brucella bacterial protein is native protein that purified from Brucella for life science related research .
    Brucella bacterial protein
  • HY-NP022
    Mycobacterium bovis bacterial protein

    Bacillus tuberculosis bovis

    		 Biochemical Assay Reagents Bacterial Infection
    Mycobacterium bovis bacterial protein is a member of the Mycobacterium tuberculosis complex. Mycobacterium bovis bacterial protein causes tuberculosis in bovines .
    Mycobacterium bovis bacterial protein

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: