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Cat. No.: HY-153518

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LpxC-IN-11

LpxC-IN-11 (Compound 1) is an LpxC inhibitor. LpxC-IN-11 can be used in the research of bacterial infectious diseases.

For research use only. We do not sell to patients.

CAS No.: 1219365-61-3
Formula: C₁₆H₂₁N₃O₄
Molecular Weight:319.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

LpxC-IN-11 Chemical Structure

CAS No.: 1219365-61-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

LpxC-IN-11 (Compound 1) is an LpxC inhibitor. LpxC-IN-11 can be used in the research of bacterial infectious diseases^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	CC₅₀	>295 μM Compound: 1(-)	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by WST1 assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by WST1 assay	[PMID: 28549219]
K562	CC₅₀	>295 μM Compound: 1(-)	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 72 hrs by WST1 assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 72 hrs by WST1 assay	[PMID: 28549219]

Chemical Information

CAS No. 1219365-61-3
Molecular Weight 319.36
Formula C₁₆H₂₁N₃O₄
SMILES

ONC([C@H](C(C)(N)C)NC(C1=CC=C(C=C1)OCC#CC)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fei Z B, et al. A scalable synthesis of a hydroxamic acid LpxC inhibitor. Organic Process Research & Development, 2012, 16(8): 1436-1441.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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