Antibacterial agent 319 

Antibacterial agent 319 is an antibacterial and antitumor agent. Antibacterial agent 319 exhibits activity against E. coli and S. aureus. Antibacterial agent 319 also inhibits the growth of melanoma cells. Antibacterial agent 319 can be used in research on tumor bacterial infections such as melanoma^[1].

Antibacterial agent 319 (Compound 7b) potently inhibits the growth of B16-F10 mouse melanoma cells with an IC₅₀ of 7.3 μM, and exhibits lower toxicity against normal HEK-293 cells (IC₅₀ = 18.4 μM)^[1].
Antibacterial agent 319 (62.5-500 μg/mL; 24 h) inhibits the growth of E. coli and S. aureus, with an MIC of 500 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

499.60

C₂₅H₃₀FN₅O₃S

O=C(NNC(CCCCCCCCCCSC1=NN=C(C2=CC=C(F)C=C2)O1)=O)C3=CC=NC=C3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Jadhaw B, et al. Novel Isoniazid-Based 1,3,4-Oxadiazole-Fatty Acid Hybrids: Synthesis, In Vitro Biological Activity and In Silico ADME/Tox Predictions. Chem Biodivers. 2026;23(1):e02042.  [Content Brief]