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United States

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Art. -Nr.: HY-181715

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PBP1b-IN-1

PBP1b-IN-1 is a penicillin-binding protein inhibitor, with an IC₅₀ of 0.042 μM against PBP1b of Streptococcus pneumoniae and an IC₅₀ of 7.6 μM against PBP3 of Escherichia coli. PBP1b-IN-1 exerts antibacterial activity by targeting penicillin-binding proteins to inhibit bacterial peptidoglycan cross-linking. PBP1b-IN-1 can be used in studies related to bacterial infections.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₂H₁₁Cl₂KN₂O₅S
Molecular Weight:405.30

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

PBP1b-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

PBP1b-IN-1 (compound 11) (30 min) potently inhibits penicillin-binding protein 1b derived from Streptococcus pneumoniae, with an IC₅₀ value of 42 nM^[1].
PBP1b-IN-1 (30 min) inhibits penicillin-binding protein 3 derived from Escherichia coli, with an IC₅₀ of 7.6 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

Molecular Weight 405.30
Formel C₁₂H₁₁Cl₂KN₂O₅S
SMILES

O=S(N1[C@@H](C)[C@H](NC(CC2=C(Cl)C=CC=C2Cl)=O)C1=O)(O[K])=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Kavaš V, et al. Structure-Activity Relationship and Crystallographic Study of New Monobactams. J Med Chem. 2026;69(4):3887-3901. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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