PBP1b-IN-1
PBP1b-IN-1 is a penicillin-binding protein inhibitor, with an IC50 of 0.042 μM against PBP1b of Streptococcus pneumoniae and an IC50 of 7.6 μM against PBP3 of Escherichia coli. PBP1b-IN-1 exerts antibacterial activity by targeting penicillin-binding proteins to inhibit bacterial peptidoglycan cross-linking. PBP1b-IN-1 can be used in studies related to bacterial infections.
For research use only. We do not sell to patients.
- Formula: C12H11Cl2KN2O5S
- Molecular Weight:405.30
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
PBP1b-IN-1 (compound 11) (30 min) potently inhibits penicillin-binding protein 1b derived from Streptococcus pneumoniae, with an IC50 value of 42 nM[1].
PBP1b-IN-1 (30 min) inhibits penicillin-binding protein 3 derived from Escherichia coli, with an IC50 of 7.6 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 405.30
-
Formula C12H11Cl2KN2O5S
-
SMILES
O=S(N1[C@@H](C)[C@H](NC(CC2=C(Cl)C=CC=C2Cl)=O)C1=O)(O[K])=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz