cCF10
cCF10 is a peptide sex pheromone. cCF10 induces transfer of the conjugative plasmid pCF10 from plasmid-containing donor cells to plasmid-free recipient cells. cCF10 induces Opp system and enters bacterial cells to inhibit (p)ppGpp accumulation. cCF10 reduces persister cell generation via maintaining the metabolically active state of bacteria.
For research use only. We do not sell to patients.
- CAS No.: 116355-81-8
- Formula: C40H67N7O9
- Molecular Weight:790.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 116355-81-8
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Molecular Weight 790.00
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Formula C40H67N7O9
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Sequence
Leu-Val-Thr-Leu-Val-Phe-Val
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Sequence Shortening
LVTLVFV
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Buttaro BA, et al. Cell-associated pheromone peptide (cCF10) production and pheromone inhibition in Enterococcus faecalis. J Bacteriol. 2000 Sep;182(17):4926-33. [Content Brief]
[2]. Zhu L, et al. Pheromone cCF10 inhibits the antibiotic persistence of Enterococcus faecalis by modulating energy metabolism. Front Microbiol. 2024 Jul 8;15:1408701. [Content Brief]
[3]. Mori M, et al. Structure of cCF10, a peptide sex pheromone which induces conjugative transfer of the Streptococcus faecalis tetracycline resistance plasmid, pCF10. J Biol Chem. 1988 Oct 5;263(28):14574-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)