AcrB-IN-1
AcrB-IN-1 (Compound H6) is a potent AcrB inhibitor. AcrB-IN-1 can be used for the reversal of bacterial multidrug resistance.
For research use only. We do not sell to patients.
- CAS No.: 2890177-82-7
- Formula: C32H39N3O4
- Molecular Weight:529.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
AcrB-IN-1 (Compound H6) is able to reduce the MIC value of tested antibacterial (Erythromycin HY-B0220, Levofloxacin HY-B0330, Minocycline HY-17412A) at sub-MIC concentrations (8-128 μg/mL) against the Escherichia coli strain BW25113[1].
AcrB-IN-1 (64 μg/mL) is shown to not disrupt the bacterial inner membrane[1].
AcrB-IN-1 completely abolishes the Nile Red (a known substrate of AcrB) efflux at a concentration of 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2890177-82-7
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Molecular Weight 529.67
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Formula C32H39N3O4
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SMILES
CC1(C)CCC2=C(O1)C3=C(C=C2C(N4CCOCC4)=O)C(OCCN5CCN(C6=CC=CC=C6)CC5)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AcrB-IN-1 Related Classifications
HY-149809 Related Classifications
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