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Cat. No.: HY-181671

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Antibacterial agent 324

Antibacterial agent 324 is an amphipathic antibacterial agent. Antibacterial agent 324 exhibits selective activity against Gram-positive bacteria, with limited activity against enterococci and weak activity against Gram-negative bacteria.

For research use only. We do not sell to patients.

Formula: C₄₆H₆₄Br₂N₄O₄
Molecular Weight:896.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antibacterial agent 324 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Antibacterial agent 324 (Compound 20a) (24 h) exhibits potent in vitro anti-Gram-positive bacterial activity, with an MIC range of 1 to 32 μg/mL. Specifically, its MIC values against Staphylococcus aureus ATCC25923 and ATCC43300 are 1 μg/mL and 2 μg/mL, respectively, and the MIC against Bacillus subtilis ATCC9372 is 2 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 896.83
Formula C₄₆H₆₄Br₂N₄O₄
SMILES

O=C(N(CCCCCC)CCCC[N+]1=CC=CC=C1)COC2=CC=C(C3=CC=C(OCC(N(CCCCCC)CCCC[N+]4=CC=CC=C4)=O)C=C3)C=C2.[Br-].[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dai N, et al. Structural optimization of natural product honokiol to discover novel membrane-targeting antibacterial agents against Gram-positive bacteria. Eur J Med Chem. 2026;307:118674. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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