FITC-D-Glucose 

FITC-D-Glucose is a fluorescently labeled glucose derivative and an orally effective bacterial metabolic activity detection probe. FITC-D-Glucose is applicable to the research of cholera^[1].

FITC-D-Glucose (1 μL in 10 mL Met-free MM medium; 30 min at 37 °C) labeling reveals that flhB mutant V. cholerae has 1.7-fold higher in vitro metabolic activity than wild-type, while flaA mutant has 0.6-fold lower in vitro metabolic activity than wild-type^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FITC-D-Glucose (0.1 mM; p.o.; single administration of 100 μL) labels metabolically active V. cholerae in adult mice. Studies show that the proportion of highly metabolically active cells in the ΔflhB mutant strain is 7 times that of the wild-type strain, while this proportion in the ΔflaA mutant strain is only 0.2 times that of the wild-type strain^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

568.55

C₂₇H₂₄N₂O₁₀S

Solid

O=C(C1=C2C=CC(NC(N[C@@H]([C@H](O)[C@@H](O)C(CO)O3)[C@H]3O)=S)=C1)OC42C5=C(C=C(O)C=C5)OC6=CC(O)=CC=C64

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Guozhong Chen, et al. Anti-σ28 factor FlgM secretion regulates Vibrio cholerae adaptability1
  in adult mice through quorum sensing and methionine metabolism.