Polymyxin B2
Based on 1 Customer Validation
Polymyxin B2 is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 is used in studies related to Pseudomonas aeruginosa infection and acute enteritis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.59%
- CAS 番号: 34503-87-2
- 分子式: C55H96N16O13
- 分子量:1189.45
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
159 μg/mL
Compound: Polymyxin B2
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Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
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[PMID: 29412662] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 34503-87-2
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性状 Solid
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分子量 1189.45
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分子式 C55H96N16O13
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Color White to off-white
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (84.07 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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- Italian - IT (252 KB)
- Korean - KR (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Han W, et al. New antimicrobial peptide-antibiotic combination strategy for Pseudomonas aeruginosa inactivation. Biointerphases. 2022;17(4):041002. Published 2022 Aug 3. [Content Brief]
[2].
Zheng L, et al. Lactiplantibacillus plantarum and Saccharomyces cerevisiae-Fermented Coconut Water Alleviates Dextran Sodium Sulfate-Induced Enteritis in Wenchang Chicken: A Gut Microbiota and Metabolomic Approach. Animals (Basel). 2024 Feb 8;14(4):575.
[Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.8407 mL | 4.2036 mL | 8.4072 mL | 21.0181 mL |
| 5 mM | 0.1681 mL | 0.8407 mL | 1.6814 mL | 4.2036 mL | |
| 10 mM | 0.0841 mL | 0.4204 mL | 0.8407 mL | 2.1018 mL | |
| 15 mM | 0.0560 mL | 0.2802 mL | 0.5605 mL | 1.4012 mL | |
| 20 mM | 0.0420 mL | 0.2102 mL | 0.4204 mL | 1.0509 mL | |
| 25 mM | 0.0336 mL | 0.1681 mL | 0.3363 mL | 0.8407 mL | |
| 30 mM | 0.0280 mL | 0.1401 mL | 0.2802 mL | 0.7006 mL | |
| 40 mM | 0.0210 mL | 0.1051 mL | 0.2102 mL | 0.5255 mL | |
| 50 mM | 0.0168 mL | 0.0841 mL | 0.1681 mL | 0.4204 mL | |
| 60 mM | 0.0140 mL | 0.0701 mL | 0.1401 mL | 0.3503 mL | |
| 80 mM | 0.0105 mL | 0.0525 mL | 0.1051 mL | 0.2627 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Polymyxin B2 関連分類
HY-A0248B 関連分類
Powered by Bioz
- Polymyxin B2
- 34503-87-2
- Polymyxin B 2
- Polymyxin B-2
- Antibiotic
- Bacterial
- Saccharomyces cerevisiae Y301
- Wenchang chicks
- Alistipes
- Pseudomonas aeruginosa PA103
- dextran sulfate sodium
- Pseudomonas aeruginosa
- acute enteritis
- Lactiplantibacillus plantarum MS2c
- LL37
- pseudomonas aeruginosa infections
- Inhibitor
- inhibitor
- inhibit