Ferrocin A
Ferrocin A is a lipopeptide compound that targets the SARS-CoV-2 RNA-dependent RNA polymerase (nsp12). Ferrocin A can stably bind to nsp12, and as an iron-chelating peptide, it reduces the concentration of free iron in the environment via complexation, thereby inhibiting bacterial growth by repressing the acquisition of essential metal cations. As an iron-chelating antiviral molecule, Ferrocin A may be used in studies related to COVID-19 and bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 114550-08-2
- Formula: C51H82FeN13O19
- Molecular Weight:1237.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 114550-08-2
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Molecular Weight 1237.12
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Formula C51H82FeN13O19
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SMILES
O=C1OCC(C(NC2C(NCC(NC(C(C)C)C(NC(CO)C(NC3C(NC(C)C(NCC(NC(CCCN4[O-][Fe+3]56(O=C(C)N(CCC2)[O-]5)(O=C(C)N(CCC3)[O-]6)O=C4C)C(NC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(C/C=C/CCCCCC)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Xia B, et al. Lipopeptides against COVID-19 RNA-dependent RNA polymerase using molecular docking. Biomed J. 2021 Dec;44(6 Suppl 1):S15-S24. [Content Brief]
[2]. Katayama N, et al. Ferrocins, new iron-containing peptide antibiotics produced by bacteria. Taxonomy, fermentation and biological activity. J Antibiot (Tokyo). 1993 Jan;46(1):65-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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