DNA Gyrase/DHFR-IN-1
DNA Gyrase/DHFR-IN-1 is a dual inhibitor of bacterial DNA gyrase and DHFR, with IC50s of 182 μM and 3.90 μM for E. coli DNA gyrase and DHFR respectively. DNA Gyrase/DHFR-IN-1 has bactericidal and antifungal activity.
For research use only. We do not sell to patients.
- Formula: C25H20N4O
- Molecular Weight:392.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DNA Gyrase/DHFR-IN-1 shows MIC values of 16 nM (B. subtilis), 24 nM (S. aureus), 51 nM(E. coli), 53 nM (P. aeruginosa), 15.50 μM (A. flavus) and 19.50 μM (C. albicans)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 392.45
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Formula C25H20N4O
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SMILES
CC1=CC=C(C2=CC(C3=CC=C(OC)C=C3)=NC4=NC(C5=CC=CC=C5)=NN24)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DNA Gyrase/DHFR-IN-1 Related Classifications
HY-168648 Related Classifications
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