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  2. Bacterial
  3. Valylleucine

Valylleucine (Val-Leu; H-Val-Leu-OH) is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration.

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Valylleucine

Valylleucine Chemical Structure

CAS No. : 3989-97-7

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Description

Valylleucine (Val-Leu; H-Val-Leu-OH) is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration[1][2].

In Vitro

Valylleucine (0.43 mM; up to 6 hours) relieves O-methylthreonine-induced growth inhibition in Escherichia coli 15 after a lag period of approximately 2 hours, matching the effectiveness of free valine and leucine thereafter[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

230.30

Formula

C11H22N2O3

CAS No.
Sequence

Val-Leu

Sequence Shortening

VL

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Valylleucine
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HY-P4668
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