2. Anti-infection Cell Cycle/DNA Damage
  3. Antibiotic Bacterial DNA/RNA Synthesis
  4. Holomycin

Holomycin is an antibiotic with dithiolopyrrolone structure. Holomycin can inhibit bacterial RNA synthesis. Holomycin has antitumor activity. Holomycin can be used for the research of bacterial infection.

For research use only. We do not sell to patients.

Holomycin

Holomycin Chemical Structure

CAS No. : 488-04-0

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Based on 1 publication(s) in Google Scholar

Holomycin Related Antibodies

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Description

Holomycin is an antibiotic with dithiolopyrrolone structure. Holomycin can inhibit bacterial RNA synthesis. Holomycin has antitumor activity. Holomycin can be used for the research of bacterial infection[1].

In Vitro

Holomycin is a broad-spectrum antibiotic that inhibits RNA synthesis in cultured Escherichia coli, acts against Rifampicin (HY-B0272)-resistant Staphylococcus aureus, and lacks activity against Saccharomyces cerevisiae[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Holomycin Related Antibodies
Molecular Weight

214.26

Formula

C7H6N2O2S2
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

CC(NC1=C2C(NC1=O)=CSS2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 95.09%

SDS (252 KB)

COA (257 KB) HNMR (196 KB) LCMS (93 KB)

Handling Instructions (2659 KB)
References
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Holomycin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Holomycin488-04-0AntibioticBacterialDNA/RNA Synthesisclavulanic acid biosynthesis genesdithiol oxidase HlmIEscherichia coliStaphylococcus aureusrifampicin-resistant mutantsRNA polymerase β-subunitYersinia ruckeriprokaryotic RNA polymeraseStreptomyces clavuligerusSaccharomyces cerevisiaeInhibitorinhibitorinhibit

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Holomycin
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HY-135751
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