Holomycin
Based on 1 Customer Validation
Holomycin is an antibiotic with dithiolopyrrolone structure. Holomycin can inhibit bacterial RNA synthesis. Holomycin has antitumor activity. Holomycin can be used for the research of bacterial infection.
For research use only. We do not sell to patients.
- Purity: 95.09%
- CAS No.: 488-04-0
- Formula: C7H6N2O2S2
- Molecular Weight:214.26
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Holomycin is a broad-spectrum antibiotic that inhibits RNA synthesis in cultured Escherichia coli, acts against Rifampicin (HY-B0272)-resistant Staphylococcus aureus, and lacks activity against Saccharomyces cerevisiae[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 488-04-0
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Appearance Solid
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Molecular Weight 214.26
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Formula C7H6N2O2S2
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Color Light yellow to brown
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SMILES
CC(NC1=C2C(NC1=O)=CSS2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Holomycin
- 488-04-0
- Antibiotic
- Bacterial
- DNA/RNA Synthesis
- clavulanic acid biosynthesis genes
- dithiol oxidase HlmI
- Escherichia coli
- Staphylococcus aureus
- rifampicin-resistant mutants
- RNA polymerase β-subunit
- Yersinia ruckeri
- prokaryotic RNA polymerase
- Streptomyces clavuligerus
- Saccharomyces cerevisiae
- Inhibitor
- inhibitor
- inhibit