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Cat. No.: HY-163734

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Tyrosinase-IN-30

Tyrosinase-IN-30 (compound 11c) is a potent tyrosinase inhibitor with an IC₅₀ value of 4.52 µM. Tyrosinase-IN-30 shows anti-bacterial activity.

For research use only. We do not sell to patients.

Formula: C₁₉H₁₇N₃O₂S
Molecular Weight:351.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tyrosinase-IN-30 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Tyrosinase-IN-30 (compound 11c) is a potent tyrosinase inhibitor with an IC₅₀ value of 4.52 µM. Tyrosinase-IN-30 shows anti-bacterial activity^[1].

IC₅₀ & Target

IC₅₀: 4.52 µM (tyrosinase)^[1]

In Vitro

Tyrosinase-IN-30 (compound 11c) shows anti-bacterial activity for Staphylococcus aureus and Escherichia coli with MIC values of 2.5, 10 mg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 351.42
Formula C₁₉H₁₇N₃O₂S
SMILES

CC(O)CSC1=NN=C(C2=CC3=CC=CC=C3O2)N1C4=CC=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Saeed S, et al. Discovery of novel 1,2,4-triazole tethered β-hydroxy sulfides as bacterial tyrosinase inhibitors: synthesis and biophysical evaluation through in vitro and in silico approaches. RSC Adv. 2024 May 13;14(22):15419-15430. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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