Gatifloxacin hydrochloride (Standard)
Gatifloxacin (hydrochloride) (Standard) is the analytical standard of Gatifloxacin (hydrochloride). This product is intended for research and analytical applications. Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml)[1]. Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 121577-32-0
- Formula: C19H23ClFN3O4
- Molecular Weight:411.86
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-13502
Mitoxantrone
-
HY-W010800
Cholesteryl hemisuccinate
-
HY-13624A
Epirubicin hydrochloride
-
HY-10581A
Gatifloxacin hydrochloride
-
HY-156376
Cu(II)-Elesclomol
-
HY-13502A
Mitoxantrone dihydrochloride
-
HY-B0125
Ofloxacin
-
HY-W010800R
Cholesteryl hemisuccinate (Standard)
-
HY-B0125R
Ofloxacin (Standard)
-
HY-13624AR
Epirubicin hydrochloride (Standard)
-
HY-13502R
Mitoxantrone (Standard)
-
HY-13502AR
Mitoxantrone dihydrochloride (Standard)
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 121577-32-0
-
Molecular Weight 411.86
-
Formula C19H23ClFN3O4
-
SMILES
CC1NCCN(C2=C(F)C=C3C(N(C4CC4)C=C(C(O)=O)C3=O)=C2OC)C1.Cl
-
Synonyms
AM-1155 hydrochloride (Standard); BMS-206584 hydrochloride (Standard); PD135432 hydrochloride (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Takei M, et al. Inhibitory activities of Gatifloxacin hydrochloride (AM-1155), a newly developed fluoroquinolone, against bacterial and mammalian type II topoisomerases.Antimicrob Agents Chemother. 1998 Oct;42(10):2678-81. [Content Brief]
[2]. Fukuda H, et al. Antibacterial activity of Gatifloxacin hydrochloride (AM-1155, CG5501, BMS-206584), a newly developed fluoroquinolone, against sequentially acquired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus. Antimicrob Agents Chemother. 1998 Aug;42(8):1917-22. [Content Brief]
[3]. Yamada C, et al. Gatifloxacin hydrochloride acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis. Eur J Pharmacol. 2006 Dec 28;553(1-3):67-72. Epub 2006 Sep 28. [Content Brief]
[4]. Daw-Garza A, et al. In vivo therapeutic effect of Gatifloxacin mesylate on BALB/c mice infected with Nocardia brasiliensis.Antimicrob Agents Chemother. 2008 Apr;52(4):1549-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gatifloxacin hydrochloride (Standard) Related Classifications
HY-10581AR Related Classifications
Powered by Bioz
- Gatifloxacin hydrochloride (Standard)
- 121577-32-0
- AM-1155 hydrochloride (Standard)
- BMS-206584 hydrochloride (Standard)
- PD135432 hydrochloride (Standard)
- Reference Standards
- Bacterial
- Topoisomerase
- Antibiotic
- E. coli,?Pseudomonas aeruginosa,?Micrococcus luteus
- S. aureus
- hypoglycemia
- hyperglycemia
- diabetic
- actinomycetoma
- N. brasiliensis
- bacterial
- conjunctivitis
- Inhibitor
- inhibitor
- inhibit