Copy Link Print Information

HADA hydrochloride

(Synonyms: HCC-Amino-D-alanine hydrochloride)
13 Cited Publications
Customer Review

Based on 13 publication(s) in Google Scholar

HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation.

For research use only. We do not sell to patients.

  • Purity: 98.01%
  • CAS No.: 2253733-10-5
  • Formula: C13H13ClN2O6
  • Molecular Weight:328.71
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)

  • HADA hydrochloride Chemical Structure
    HADA hydrochloride Chemical Structure
  • Experimental Validation Results for HADA hydrochloride
  • Experimental Validation Results for HADA hydrochloride
  • Experimental Validation Results for HADA hydrochloride
  • Experimental Validation Results for HADA hydrochloride
CAS No.: 2253733-10-5
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of HADA hydrochloride:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Purity & Documentation
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) HADA hydrochloride

More
Customer Validation & Images
Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • HADA hydrochloride Chemical Structure
    HADA hydrochloride Chemical Structure
    1/16
  • 1/16

    HADA hydrochloride purchased from MedChemExpress. Usage Cited in: Microbiol Res. 2025 Sep 24:302:128350. [Abstract]

    Customer Validation
     Fluorescence microscopy of AR-GBS labeled with HADA hydrochloride (250 μM; 30 min) following treatment with 20 mM PAG plus 1/4 MIC AMP.

  • 1/16

    HADA hydrochloride purchased from MedChemExpress. Usage Cited in: Pharmaceuticals (Basel). 2025 Sep 28;18(10):1458. [Abstract]

    Customer Validation
     The impact of BA in combination with KM on bacterial peptidoglycan synthesis was tracked using HADA hydrochloride (250 μM; 30 min). Peptidoglycan synthesis in MRSA USA300 and Staphylococcus aureus ATCC29213, observed via confocal laser scanning microscopy (CLSM). Scale bar = 5 μm. The regions of interest are marked by white circles, where a decrease in fluorescence intensity and abnormal morphology of some cells can be observed.

  • 1/16

    HADA hydrochloride purchased from MedChemExpress. Usage Cited in: mBio. 2025 Apr 9;16(4):e0297524. [Abstract]

    Customer Validation
     Ampicillin affects the incorporation of newly synthesized cell wall in PG recycling mutants. HADA labeling of strains CB15N, RP47 (∆sdpA), and RP56 (∆ampG) in the presence (+ amp) and absence (- amp) of ampicillin. Overnight cultures were diluted in PYE media, grown to 0.1 OD600, and treated with 40 µg/mL ampicillin for 4 h. Cells were collected, washed with minimal media, and incubated with 0.5 mM HADA hydrochloride for 15 min at 30°C. Cells were washed with minimal media again and imaged using a Nikon Fluorescence Microscope CFP filter. A representative cell (yellow arrowheads) was selected from each strain condition shown, and their fluorescence profiles were extracted along the cell length axis. Fluorescence intensity (arbitrary units [a.u.]) is plotted against the position along the entire cell length (scale bar = 3 µm).

  • 1/16

    HADA hydrochloride purchased from MedChemExpress. Usage Cited in: mBio. 2024 Jun 12;15(6):e0067924. [Abstract]

    Customer Validation
     S. aureus cells expressing Gp11 or its mutants were stained with the fluorescent cell wall marker HADA hydrochloride (250 μM; 30 min) and analyzed by phase-contrast and fluorescence microscopy. The results showed that compared to controls, Gp11 overexpression resulted in a more diffuse HADA signal localized to​ multiple intracellular sites, including the cell periphery and partial septa. Scale bars, 2.5 µm.

  • HADA hydrochloride