Lytx-Pa2a
Lytx-Pa2a (Lycotoxin-Pa2a) is a peptide inhibitor against bacterial membranes and TLR4 receptor. Lytx-Pa2a exerts antimicrobial effects via non-competitive disruption of outer/cytoplasmic membranes and suppression of LPS-induced TLR4/NF-κB signaling. Lytx-Pa2a is promising for research of bacterial infection and inflammation-related disease (e.g., sepsis).
For research use only. We do not sell to patients.
- Formula: C314H494N94O91S8
- Molecular Weight:7298.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TLR4 |
Chemical Information
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Molecular Weight 7298.38
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Formula C314H494N94O91S8
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Synonyms
Lycotoxin-Pa2a; TBIU041425
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Sequence
Lys-Glu-Cys-Ile-Pro-Lys-His-His-Glu-Cys-Thr-Ser-Asn-Lys-Lys-Gly-Cys-Cys-Arg-Gly-Lys-Leu-Phe-Lys-Tyr-Lys-Cys-Gln-Cys-Thr-Thr-Val-Val-Asp-Gln-Ser-Gly-Glu-Gln-Ala-Glu-Arg-Cys-Phe-Cys-Gly-Thr-Ala-Thr-His-His-Lys-Ala-Ala-Glu-Leu-Val-Val-Gly-Phe-Gly-Lys-Lys-Leu-Phe-Gly (disulfide bridge:Cys3-Cys18,Cys10-Cys27,Cys17-Cys45,Cys29-Cys43)
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Sequence Shortening
KECIPKHHECTSNKKGCCRGKLFKYKCQCTTVVDQSGEQAERCFCGTATHHKAAELVVGFGKKLFG (disulfide bridge:Cys3-Cys18,Cys10-Cys27,Cys17-Cys45,Cys29-Cys43)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)