1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Ceftizoxime sodium

Ceftizoxime sodium (Synonyms: SKF-88373)

Cat. No.: HY-B1596A Purity: 99.76%
Handling Instructions

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

For research use only. We do not sell to patients.

Ceftizoxime sodium Chemical Structure

Ceftizoxime sodium Chemical Structure

CAS No. : 68401-82-1

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Free Sample (0.5-1 mg)   Apply Now  
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg USD 96 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Description

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

IC50 & Target

Antibacterial

In Vitro

Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

405.38

Formula

C₁₃H₁₂N₅NaO₅S₂

CAS No.

68401-82-1

SMILES

O=C(C(N12)=CCS[[email protected]]2([H])[[email protected]](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 15 mg/mL (37.00 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4668 mL 12.3341 mL 24.6682 mL
5 mM 0.4934 mL 2.4668 mL 4.9336 mL
10 mM 0.2467 mL 1.2334 mL 2.4668 mL
*Please refer to the solubility information to select the appropriate solvent.
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Keywords:

CeftizoximeSKF-88373SKF88373SKF 88373BacterialAntibioticInhibitorinhibitorinhibit

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Product Name:
Ceftizoxime sodium
Cat. No.:
HY-B1596A
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