Ceftizoxime sodium
Based on 1 publication(s) in Google Scholar
Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 68401-82-1
- Formula: C13H12N5NaO5S2
- Molecular Weight:405.38
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Storage:
4°C, sealed storage, away from moisture
* The compound is unstable in solutions, freshly prepared is recommended.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Ceftizoxime sodium
MoreAll Antibiotic Isoforms
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Biological Activity
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β-lactam |
Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 68401-82-1
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Appearance Solid
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Molecular Weight 405.38
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Formula C13H12N5NaO5S2
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Color White to off-white
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SMILES
O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O[Na]
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Synonyms
SKF-88373
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* The compound is unstable in solutions, freshly prepared is recommended.
Publications (1)
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Journal Impact Factor
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Most Recent
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Nat Commun
2023 Mar 22;14(1):1594. PMID: 36949052
Solvent & Solubility
H2O : 100 mg/mL (246.68 mM; Need ultrasonic)
DMSO : 15 mg/mL (37.00 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (251 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.4668 mL | 12.3341 mL | 24.6682 mL | 61.6705 mL |
| 5 mM | 0.4934 mL | 2.4668 mL | 4.9336 mL | 12.3341 mL | |
| 10 mM | 0.2467 mL | 1.2334 mL | 2.4668 mL | 6.1671 mL | |
| 15 mM | 0.1645 mL | 0.8223 mL | 1.6445 mL | 4.1114 mL | |
| 20 mM | 0.1233 mL | 0.6167 mL | 1.2334 mL | 3.0835 mL | |
| 25 mM | 0.0987 mL | 0.4934 mL | 0.9867 mL | 2.4668 mL | |
| 30 mM | 0.0822 mL | 0.4111 mL | 0.8223 mL | 2.0557 mL | |
| H2O | 40 mM | 0.0617 mL | 0.3084 mL | 0.6167 mL | 1.5418 mL |
| 50 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2334 mL | |
| 60 mM | 0.0411 mL | 0.2056 mL | 0.4111 mL | 1.0278 mL | |
| 80 mM | 0.0308 mL | 0.1542 mL | 0.3084 mL | 0.7709 mL | |
| 100 mM | 0.0247 mL | 0.1233 mL | 0.2467 mL | 0.6167 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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