1. Anti-infection
  2. Bacterial Antibiotic
  3. Ceftizoxime sodium

Ceftizoxime sodium  (Synonyms: SKF-88373)

Cat. No.: HY-B1596A Purity: 99.77%
COA Handling Instructions

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

For research use only. We do not sell to patients.

Ceftizoxime sodium Chemical Structure

Ceftizoxime sodium Chemical Structure

CAS No. : 68401-82-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Ceftizoxime sodium:

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1 Publications Citing Use of MCE Ceftizoxime sodium

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Description

Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

IC50 & Target

β-lactam

 

In Vitro

Ceftizoxime is a third-generation cephalosporin available for parenteral administration. Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. It rather resembles cefotaxime in its properties, but is not subject to metabolism.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

405.38

Appearance

Solid

Formula

C13H12N5NaO5S2

CAS No.
SMILES

O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (246.68 mM; Need ultrasonic)

DMSO : 15 mg/mL (37.00 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4668 mL 12.3341 mL 24.6682 mL
5 mM 0.4934 mL 2.4668 mL 4.9336 mL
10 mM 0.2467 mL 1.2334 mL 2.4668 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Ceftizoxime sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Ceftizoxime sodium
Cat. No.:
HY-B1596A
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