(R)-Gyramide A hydrochloride

Cat. No.: HY-109785A: Ficha de datos Instrucciones de manejo
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(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC₅₀ value of 3.3 µM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 µM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV.

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(R)-Gyramide A hydrochloride Estructura química

No. CAS : 1793050-70-0

Tamaño	Stock	Cantidad
1 mg	Obtener un presupuesto 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	Obtener un presupuesto
10 mg	Obtener un presupuesto

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Descripciòn	(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC₅₀ value of 3.3 µM. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 µM). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV.
Peso molecular	442.98
Fòrmula	C₂₁H₂₈ClFN₂O₃S
No. CAS	1793050-70-0
SMILES	O=S(C1=CC(F)=CC=C1C)(N[C@H]2CN(CC3=CC=C(OC(C)C)C=C3)CC2)=O.[H]Cl
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (267 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Foss MH, et al. N-Benzyl-3-sulfonamidopyrrolidines are a New Class of Bacterial DNA Gyrase Inhibitors. ACS Med Chem Lett. 2011 Apr 14;2(4):289-292. [Content Brief]