1. Tobramycin sulfate

Tobramycin sulfate  (Synonyms: Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate)

Cat. No.: HY-B0441A Purity: ≥98.0%
COA Handling Instructions

Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.

For research use only. We do not sell to patients.

Tobramycin sulfate Chemical Structure

Tobramycin sulfate Chemical Structure

CAS No. : 49842-07-1

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100 mg USD 60 In-stock
500 mg USD 120 In-stock
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5 g   Get quote  

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Based on 5 publication(s) in Google Scholar

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Description

Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].

Clinical Trial
Molecular Weight

712.18

Formula

C18H37N5O9.5/2H2O4S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(O)(O)=O.OC[C@H]([C@@H](O)[C@H](N)[C@H]1O)O[C@]1([H])O[C@@H]2[C@H]([C@@H]([C@@H](N)C[C@H]2N)O[C@@]3([H])O[C@@H]([C@@H](O)C[C@H]3N)CN)O.[5/2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (351.03 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4041 mL 7.0207 mL 14.0414 mL
5 mM 0.2808 mL 1.4041 mL 2.8083 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4041 mL 7.0207 mL 14.0414 mL 35.1035 mL
5 mM 0.2808 mL 1.4041 mL 2.8083 mL 7.0207 mL
10 mM 0.1404 mL 0.7021 mL 1.4041 mL 3.5103 mL
15 mM 0.0936 mL 0.4680 mL 0.9361 mL 2.3402 mL
20 mM 0.0702 mL 0.3510 mL 0.7021 mL 1.7552 mL
25 mM 0.0562 mL 0.2808 mL 0.5617 mL 1.4041 mL
30 mM 0.0468 mL 0.2340 mL 0.4680 mL 1.1701 mL
40 mM 0.0351 mL 0.1755 mL 0.3510 mL 0.8776 mL
50 mM 0.0281 mL 0.1404 mL 0.2808 mL 0.7021 mL
60 mM 0.0234 mL 0.1170 mL 0.2340 mL 0.5851 mL
80 mM 0.0176 mL 0.0878 mL 0.1755 mL 0.4388 mL
100 mM 0.0140 mL 0.0702 mL 0.1404 mL 0.3510 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tobramycin sulfate
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HY-B0441A
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