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製品番号: HY-133161

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RhlR agonist-1

RhlR agonist-1 is a N-acylated L-homoserine lactone and is a selective quorum sensing receptor RhlR agonist. RhlR agonist-1 can be used for the research of bacterial infections.

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CAS 番号: 1061591-41-0
分子式: C₁₀H₁₅NO₃
分子量:197.23

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

RhlR agonist-1 構造式

CAS 番号: 1061591-41-0

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

RhlR agonist-1 is a N-acylated L-homoserine lactone and is a selective quorum sensing receptor RhlR agonist. RhlR agonist-1 can be used for the research of bacterial infections^[1].

体外実験

RhlR agonist-1 (Compound S4) (100 nM-1 mM) potently activates RhlR in recombinant E. coli JLD271 with an EC₅₀ of 2.8 μM, inducing 91% of the maximum RhlR activity seen with the native ligand BHL at 100 μM^[1].
RhlR agonist-1 potently activates RhlR in P. aeruginosa PAO-JP2 with an EC₅₀ of 4.5 μM, inducing 105% of the maximum RhlR activity seen with the native ligand BHL at 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1061591-41-0
分子量 197.23
分子式 C₁₀H₁₅NO₃
SMILES

N(C(=O)C1CCCC1)[C@@H]2C(=O)OCC2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Eibergen NR, et al. Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosa. Chembiochem. 2015;16(16):2348-2356. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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