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  3. Bisdionin C

Bisdionin C 

Cat. No.: HY-115661
Handling Instructions

Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively.

For research use only. We do not sell to patients.

Bisdionin C Chemical Structure

Bisdionin C Chemical Structure

CAS No. : 74857-22-0

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Description

Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1].

IC50 & Target

GH18 Chitinases[1]

Molecular Weight

400.39

Formula

C₁₇H₂₀N₈O₄

CAS No.

74857-22-0

SMILES

O=C(N1CCCN2C(N(C)C3=C(N(C)C=N3)C2=O)=O)N(C)C4=C(N(C)C=N4)C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Bisdionin CBacterialbacterialtypepathogenicorganismsAfChiB1Inhibitorinhibitorinhibit

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