74857-22-0
74857-22-0
Chemical Structure
Bisdionin C
- CAS No.: 74857-22-0
- Formula:C17H20N8O4
- Molecular Weight:400.39
IUPAC Name: 1,1'-(propane-1,3-diyl)bis(3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione)
InChIKey: KEPIKAFUZRKZMT-UHFFFAOYSA-N
SMILES: O=C(N1CCCN2C(N(C)C3=C(N(C)C=N3)C2=O)=O)N(C)C4=C(N(C)C=N4)C1=O
Biological Activity: Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bisdionin C | 98.97% | Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively. | ||||||||||||||||||||
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References
Keywords
