NTPDase-IN-1
NTPDase-IN-1 (compound 5a) is a selective NTPDase inhibitor with IC50s of 0.05, 0.23 and 0.54 µM for h-NTPDase-1/-2/-8, respectively. NTPDase-IN-1 non-competitively inhibits h-NTPDase-1/-2 with a Km of 21 µM for h-NTPDase-1. NTPDase-IN-1 can be used in studies of cancer, immunologic disorders as well as bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 2962812-29-7
- Formula: C18H25N3OS2
- Molecular Weight:363.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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h-NTPDase-1 0.05 μM (IC50) |
h-NTPDase-2 0.23 μM (IC50) |
h-NTPDase-8 0.54 μM (IC50) |
h-NTPDase-3 >100 μM (IC50) |
Chemical Information
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CAS No. 2962812-29-7
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Molecular Weight 363.54
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Formula C18H25N3OS2
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SMILES
CCCSC1=NN=C(S1)NC(C(C2=CC=C(C=C2)CC(C)C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)