1. Signaling Pathways
  2. Immunology/Inflammation
  3. NTPDase
  4. NTPDase2 Isoform

NTPDase2

 

NTPDase2 Related Products (2):

Cat. No. Product Name Effect Purity
  • HY-D0976
    NF279
    Inhibitor 98.5%
    NF279 is a selective P2X1 receptor antagonist and NTPDase inhibitor, with a P2X1 IC50 value of 19 nM. NF279 suppresses GABA-evoked currents, reduces ATP-excited respiratory activity, alters hypoglossal nerve burst parameters, and blocks CXCR4, CCR5, CXCR3, and CXCR7-mediated calcium responses. NF279 arrests HIV-1 fusion downstream of CD4 binding, inhibits R5- and X4-tropic HIV-1 strains. NF279 can be used for the research of HIV-1 infection.
  • HY-120566
    PSB-16131
    Inhibitor 99.94%
    PSB-16131 is a potent inhibitor of human NTPDase2, showing non-competitive inhibition with an IC50 of 539 nM. PSB-16131 can be used in the study of inflammation, neurodegenerative diseases and cancer.