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Cat. No.: HY-106257S

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Ceftolozane-d₆ TFA

Name: Ceftolozane-d6 TFA
Brand: MedChemExpress
SKU: HY-106257S
Price: 2850.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Ceftolozane-d₆ TFA is the deuterated-labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections.

For research use only. We do not sell to patients.

Formula: C₂₅H₂₅D₆F₃N₁₂O₁₀S₂
Molecular Weight:786.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (283 KB)

Ceftolozane-d₆ TFA Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Application
Chemical Information
Purity & Documentation
References
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Classifications
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Biological Activity

Description

All Antibiotic Isoforms :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 1628046-32-1
Molecular Weight 786.75
Formula C₂₅H₂₅D₆F₃N₁₂O₁₀S₂
SMILES

[O-]C(C(F)(F)F)=O.OC(C1=C(C[N+]2=CC(NC(NCCN)=O)=C(N2C)N)CS[C@@]([C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C(O)=O)=O)([H])N1C3=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (283 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gu, J.-Q., et al. (2016, February 25). Salt forms of ceftolozane. World Intellectual Property Organization. WO 2016/028670 A1.

[2]. Martens-Lobenhoffer J, et al. Stability of ceftolozane in human plasma and dried blood spots: Implications for transport and storage. Journal of pharmacological and toxicological methods. 2020;103:106692.

[3]. Yu B, et al. Safety, Tolerability, and Pharmacokinetics of 3 g of Ceftolozane/Tazobactam in Healthy Adults: A Randomized, Placebo-Controlled, Multiple-Dose Study. Clinical pharmacology in drug development. 2018 May;7(4):382-391. [Content Brief]

[4]. Knappe D, et al. Oncocin Onc72 is efficacious against antibiotic-susceptible Klebsiella pneumoniae ATCC 43816 in a murine thigh infection model. Biopolymers. 2015 Nov;104(6):707-11.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Purity & Documentation
References

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Ceftolozane-d6 TFA

All Antibiotic Isoforms

Biological Activity

Description

Application

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ceftolozane-d6 TFA Related Classifications

HY-106257S Related Classifications

Bioz

Keywords

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