Citrocin
Citrocin is a potent bacterial RNA polymerase (RNAP) inhibitor. Citrocin shows significant inhibitory activity against Escherichia coli RNAP with an MIC range of 16-125 μM. Citrocin specifically binds to and inhibits RNA polymerase to block bacterial transcription and enters cells mainly through inner membrane protein SbmA. Citrocin is promising for research of Gram-negative bacterial infections, such as enterohemorrhagic E. coli.
For research use only. We do not sell to patients.
- Formula: C88H133N23O23
- Molecular Weight:1881.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
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RNA Polymerase |
Chemical Information
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Molecular Weight 1881.14
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Formula C88H133N23O23
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Sequence
cyclo{Gly-Gly-Val-Gly-Lys-Ile-Ile-Glu}-Tyr-Phe-Ile-Gly-Gly-Gly-Val-Gly-Arg-Tyr-Gly
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Sequence Shortening
cyclo{GGVGKIIE}YFIGGGVGRYG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)