Acetyl phosphate lithium potassium
Based on 1 publication(s) in Google Scholar
Acetyl phosphate lithium potassium is an endogenous metabolic product. Acetyl phosphate lithium potassium is a key substance in bacterial metabolic regulation, particularly in Lysine acetylation, and plays an important role in bacterial responses to environmental stress and adaptive reactions.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 94249-01-1
- Formula: C2H3KLiO5P
- Molecular Weight:184.06
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Acetyl phosphate lithium potassium
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Biological Activity
Acetyl-Phosphate (10 mM) lithium potassium is an important regulator of lysine acetylation in Escherichia coli. Its role in E. coli primarily involves regulating lysine acetylation, promoting protein function regulation, influencing metabolic activities, and affecting cell growth states[1]. Acetyl-Phosphate (1-10 mM, 30 minutes) non-enzymatically regulates lysine acetylation of Salmonella typhimurium PhoP protein, playing a crucial role in bacterial responses to various environmental stresses[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 94249-01-1
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Appearance Solid
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Molecular Weight 184.06
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Formula C2H3KLiO5P
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Color White to off-white
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SMILES
O=P(O[Li])(O[K])OC(C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
H2O : 31.25 mg/mL (169.78 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (543.30 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (275 KB)
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SDS (641 KB)
- English - EN (641 KB)
- Français - FR (641 KB)
- Deutsch - DE (641 KB)
- Norwegian - NO (641 KB)
- Español - ES (641 KB)
- Swedish - SV (641 KB)
- Italian - IT (641 KB)
- Korean - KR (641 KB)
- Portuguese - PT (641 KB)
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Handling Instructions (2659 KB)
References
[1]. Weinert BT, et al. Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli. Mol Cell. 2013 Jul 25;51(2):265-72. [Content Brief]
[2]. Ren J, et al. Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation. Emerg Microbes Infect. 2019;8(1):55-69. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.4330 mL | 27.1651 mL | 54.3301 mL | 135.8253 mL |
| 5 mM | 1.0866 mL | 5.4330 mL | 10.8660 mL | 27.1651 mL | |
| 10 mM | 0.5433 mL | 2.7165 mL | 5.4330 mL | 13.5825 mL | |
| 15 mM | 0.3622 mL | 1.8110 mL | 3.6220 mL | 9.0550 mL | |
| 20 mM | 0.2717 mL | 1.3583 mL | 2.7165 mL | 6.7913 mL | |
| 25 mM | 0.2173 mL | 1.0866 mL | 2.1732 mL | 5.4330 mL | |
| 30 mM | 0.1811 mL | 0.9055 mL | 1.8110 mL | 4.5275 mL | |
| 40 mM | 0.1358 mL | 0.6791 mL | 1.3583 mL | 3.3956 mL | |
| 50 mM | 0.1087 mL | 0.5433 mL | 1.0866 mL | 2.7165 mL | |
| 60 mM | 0.0906 mL | 0.4528 mL | 0.9055 mL | 2.2638 mL | |
| 80 mM | 0.0679 mL | 0.3396 mL | 0.6791 mL | 1.6978 mL | |
| 100 mM | 0.0543 mL | 0.2717 mL | 0.5433 mL | 1.3583 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.