Adamantane-carboxylic acid
Based on 1 Customer Validation
Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 828-51-3
- Formula: C11H16O2
- Molecular Weight:180.25
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Adamantane-carboxylic acid (1000-1500 mg/mL; 24 h) in the antibacterial experiment can effectively inhibit the growth of Gram-positive bacteria, and has a weaker inhibitory effect on Gram-negative bacteria.
At a concentration of 1000 mg/mL, it can completely stop the growth of Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Micrococcus luteus and Citrobacter freundii. At 1500 mg/mL, no growth of Staphylococcus aureus and Pseudomonas aeruginosa is observed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 828-51-3
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Appearance Solid
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Molecular Weight 180.25
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Formula C11H16O2
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Color White to light yellow
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SMILES
OC(C12C[C@H]3C[C@@H](C2)C[C@@H](C1)C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (554.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.5479 mL | 27.7397 mL | 55.4794 mL | 138.6986 mL |
| 5 mM | 1.1096 mL | 5.5479 mL | 11.0959 mL | 27.7397 mL | |
| 10 mM | 0.5548 mL | 2.7740 mL | 5.5479 mL | 13.8699 mL | |
| 15 mM | 0.3699 mL | 1.8493 mL | 3.6986 mL | 9.2466 mL | |
| 20 mM | 0.2774 mL | 1.3870 mL | 2.7740 mL | 6.9349 mL | |
| 25 mM | 0.2219 mL | 1.1096 mL | 2.2192 mL | 5.5479 mL | |
| 30 mM | 0.1849 mL | 0.9247 mL | 1.8493 mL | 4.6233 mL | |
| 40 mM | 0.1387 mL | 0.6935 mL | 1.3870 mL | 3.4675 mL | |
| 50 mM | 0.1110 mL | 0.5548 mL | 1.1096 mL | 2.7740 mL | |
| 60 mM | 0.0925 mL | 0.4623 mL | 0.9247 mL | 2.3116 mL | |
| 80 mM | 0.0693 mL | 0.3467 mL | 0.6935 mL | 1.7337 mL | |
| 100 mM | 0.0555 mL | 0.2774 mL | 0.5548 mL | 1.3870 mL |