1. Apoptosis
  2. Bcl-2 Family
  3. Mcl1-IN-2

Mcl1-IN-2 

Cat. No.: HY-12826 Purity: >95.0%
Handling Instructions

Mcl1-IN-2 is an inhibitor of myeloid cell factor 1 (Mcl-1).

For research use only. We do not sell to patients.

Mcl1-IN-2 Chemical Structure

Mcl1-IN-2 Chemical Structure

CAS No. : 292057-76-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 264 In-stock
Estimated Time of Arrival: December 31
5 mg USD 240 In-stock
Estimated Time of Arrival: December 31
10 mg USD 400 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Mcl1-IN-2 is an inhibitor of myeloid cell factor 1 (Mcl-1).

IC50 & Target[1]

Mcl-1

 

In Vitro

Mcl1-IN-2 (Compound 2) is a Mcl-1 inhibitor, though without a reported IC50 value[1].

Molecular Weight

333.41

Formula

C₁₉H₁₅N₃OS

CAS No.

292057-76-2

SMILES

OC1=C(N=CC=C2)C2=CC=C1C(NC3=CC=CC=N3)C4=CC=CS4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (99.97 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9993 mL 14.9966 mL 29.9931 mL
5 mM 0.5999 mL 2.9993 mL 5.9986 mL
10 mM 0.2999 mL 1.4997 mL 2.9993 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.50 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Mcl1-IN-2Bcl-2 FamilyInhibitorinhibitorinhibit

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Product Name:
Mcl1-IN-2
Cat. No.:
HY-12826
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