Urease-IN-11
Urease-IN-11 (Compound 6e) is a competitive urease inhibitor (IC50)=10.41 µM). Urease-IN-11 can be used to study diseases such as urease-related gastritis and peptic ulcer.
For research use only. We do not sell to patients.
- CAS No.: 517906-12-6
- Formula: C21H15N5S
- Molecular Weight:369.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Urease[1].
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H157 | IC50 |
4.32 μM
Compound: 6e
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Cytotoxicity against human NCI-H157 cells by sulforhodamine B assay
Cytotoxicity against human NCI-H157 cells by sulforhodamine B assay
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[PMID: 25257911] |
Chemical Information
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CAS No. 517906-12-6
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Molecular Weight 369.44
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Formula C21H15N5S
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SMILES
C1(C2=NN=C3N2N=C(C4=CC=C(C5=CC=CC=C5)C=C4)CS3)=CC=CN=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ullah S, et al. Urease inhibitory potential of pyridine-containing triazolothiadiazole and triazolothiadiazine scaffolds for the treatment of ulceration and kidney stone: in vitro screening, kinetics mechanism, and in silico computational analysis. J Biomol Struct Dyn. 2023 Dec 28:1-10. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Urease-IN-11 Related Classifications
HY-162139 Related Classifications
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