1. Metabolic Enzyme/Protease
    Others
  2. Endogenous Metabolite
    Others
  3. Dimethyl sulfone

Dimethyl sulfone  (Synonyms: Methyl Sulfonyl Methane)

Cat. No.: HY-Y1314 Purity: 99.81%
COA Handling Instructions

Dimethyl sulfone (DMSO, Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective.

For research use only. We do not sell to patients.

Dimethyl sulfone Chemical Structure

Dimethyl sulfone Chemical Structure

CAS No. : 67-71-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 g USD 50 In-stock
Estimated Time of Arrival: December 31
50 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Dimethyl sulfone

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Dimethyl sulfone (DMSO, Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

Dimethyl sulfone (25 mM/mL for 15.5 μL/mL; 24 h) inhibits the proliferation of cultured bovine choriocapillary endothelial (CCE) cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Dimethyl sulfone (for 0, 0.01, 0.03, 0.1, 0.3 and 1.0 mL; i.p.; single dose) shows neuroprotective effect with significant infarction volume reduction in ischemia rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

94.13

Formula

C2H6O2S

CAS No.
SMILES

O=S(C)(C)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (531.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.6236 mL 53.1180 mL 106.2361 mL
5 mM 2.1247 mL 10.6236 mL 21.2472 mL
10 mM 1.0624 mL 5.3118 mL 10.6236 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Dimethyl sulfone
Cat. No.:
HY-Y1314
Quantity:
MCE Japan Authorized Agent: