Dimethyl sulfone
Based on 3 publication(s) in Google Scholar
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective.
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 67-71-0
- Formula: C2H6O2S
- Molecular Weight:94.13
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Dimethyl sulfone
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Biological Activity
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Microbial Metabolite |
Human Endogenous Metabolite |
Dimethyl sulfone (25 mM/mL for 15.5 μL/mL; 24 h) inhibits the proliferation of cultured bovine choriocapillary endothelial (CCE) cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 67-71-0
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Appearance Solid
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Molecular Weight 94.13
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Formula C2H6O2S
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Color White to off-white
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SMILES
O=S(C)(C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (3)
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Journal Impact Factor
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Most Recent
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ACS Environ Au
Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution. [Abstract]2025 Aug 5;5(6):573-582. PMID: 41277996 -
Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576 -
J Cardiovasc Transl Res
Sacubitril/Valsartan Decreases Atrial Fibrillation Susceptibility by Inhibiting Angiotensin II-Induced Atrial Fibrosis Through p-Smad2/3, p-JNK, and p-p38 Signaling Pathways. [Abstract]2022 Feb;15(1):131-142. PMID: 34075552
Solvent & Solubility
H2O : 50 mg/mL (531.18 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Dimethyl Sulfone. 2022 Mar 21. [Content Brief]
[2]. Eter N, et al. DMSO mimics inhibitory effect of thalidomide on choriocapillary endothelial cell proliferation in culture. Br J Ophthalmol. 2002 Nov;86(11):1303-5. [Content Brief]
[3]. Shimizu S, et al. Dimethylsulfoxide (DMSO) treatment reduces infarction volume after permanent focal cerebral ischemia in rats. Neurosci Lett. 1997 Dec 19;239(2-3):125-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 10.6236 mL | 53.1180 mL | 106.2361 mL | 265.5901 mL |
| 5 mM | 2.1247 mL | 10.6236 mL | 21.2472 mL | 53.1180 mL | |
| 10 mM | 1.0624 mL | 5.3118 mL | 10.6236 mL | 26.5590 mL | |
| 15 mM | 0.7082 mL | 3.5412 mL | 7.0824 mL | 17.7060 mL | |
| 20 mM | 0.5312 mL | 2.6559 mL | 5.3118 mL | 13.2795 mL | |
| 25 mM | 0.4249 mL | 2.1247 mL | 4.2494 mL | 10.6236 mL | |
| 30 mM | 0.3541 mL | 1.7706 mL | 3.5412 mL | 8.8530 mL | |
| 40 mM | 0.2656 mL | 1.3280 mL | 2.6559 mL | 6.6398 mL | |
| 50 mM | 0.2125 mL | 1.0624 mL | 2.1247 mL | 5.3118 mL | |
| 60 mM | 0.1771 mL | 0.8853 mL | 1.7706 mL | 4.4265 mL | |
| 80 mM | 0.1328 mL | 0.6640 mL | 1.3280 mL | 3.3199 mL | |
| 100 mM | 0.1062 mL | 0.5312 mL | 1.0624 mL | 2.6559 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Dimethyl sulfone Related Classifications
HY-Y1314 Related Classifications
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