2. Anti-infection
  3. Bacterial Antibiotic Penicillin-binding protein (PBP)
  4. Moenomycin complex

Moenomycin complex is a class of antibacterial agents and PBP inhibitors, with Kd values ranging from 94 nM to 1690 nM against various bacterial PBPs. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs). Moenomycin complex is used in the research of bacterial infections.

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Moenomycin complex

Moenomycin complex Chemical Structure

CAS No. : 11015-37-5

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Moenomycin complex Related Antibodies

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Description

Moenomycin complex is a class of antibacterial agents and PBP inhibitors, with Kd values ranging from 94 nM to 1690 nM against various bacterial PBPs. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs). Moenomycin complex is used in the research of bacterial infections[1].

IC50 & Target

Transglycosylase[1]
In Vitro

Moenomycin complex binds to full-length class A PBPs from 16 bacterial species, with Kd values ranging from 94 nM (Enterococcus faecium PBP1) to 1690 nM (Bacillus subtilis PBP1a/1b)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Moenomycin complex Related Antibodies
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

[Moenomycin complex]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 25 mg/mL (Need ultrasonic and warming)

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Purity & Documentation

Purity: 99.9%

SDS (394 KB)

COA (241 KB)

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Moenomycin complex Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Moenomycin complex11015-37-5BacterialAntibioticPenicillin-binding protein (PBP)Helicobacter pyloriEnterococcus faecalistransglycosylase activityEscherichia coli PBP1bEnterococcus faecium PBP1bacterial cell wall synthesisBacillus subtilis PBP1a/1bStaphylococcus aureusGram-positive bacteriapenicillin-binding proteinInhibitorinhibitorinhibit

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Moenomycin complex
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