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Cat. No.: HY-109135

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Pravibismane

Name: Pravibismane
Brand: MedChemExpress
SKU: HY-109135
Price: 250.00 USD
Availability: PreOrder

(Synonyms: BisEDT; MBN-101)

Pravibismane (BisEDT; MBN-101) is a broad-spectrum topical anti-infective and anti-biofilm agent. Pravibismane disrupts bacterial bioenergetics by reducing bacterial concentrations of ATP in both planktonic and biofilm phenotypes and exhibits potent anti-biofilm activity against diabetic foot infections (DFI)-relevant pathogens, such as S. aureus and P. aeruginosa. Pravibismane can be used for the study of diabetic foot infections.

For research use only. We do not sell to patients.

Purity : 98.0%
CAS No.: 175880-68-9
Formula: C₆H₁₂Bi₂S₆
Molecular Weight:694.51

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Pravibismane Chemical Structure

CAS No.: 175880-68-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 175880-68-9
Appearance Solid
Molecular Weight 694.51
Formula C₆H₁₂Bi₂S₆
Color Light yellow to yellow
SMILES

[Bi]1(SCCS1)SCCS[Bi]2SCCS2
Synonyms

BisEDT; MBN-101
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lipsky BA, et al. Topical pravibismane as adjunctive therapy for moderate or severe diabetic foot infections: A phase 1b randomized, multicenter, double-blind, placebo-controlled trial. Int Wound J. 2024 Apr;21(4):e14817. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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