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Cat. No.: HY-W587701

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Methacycline

2 Cited Publications

고객리뷰

Based on 2 publication(s) in Google Scholar

Methacycline is a tetracycline antibiotic that inhibits bacterial protein synthesis. Methacycline is a potent inhibitor of epithelial-to-mesenchymal transition (EMT). Methacycline blocks EMT in vitro and inhibits fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling. Methacycline is an antimicrobial agent with potential for use in pulmonary fibrosis research.

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CAS No.: 914-00-1
화학식: C₂₂H₂₂N₂O₈
분자량:442.42

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Methacycline Chemical Structure

CAS No.: 914-00-1

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Chemical Information

CAS No. 914-00-1
분자량 442.42
화학식 C₂₂H₂₂N₂O₈
SMILES

O[C@]12[C@]([C@H]([C@@]3([H])C(C(C4=C(O)C=CC=C4C3=C)=O)=C2O)O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C
선적

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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EBioMedicine

A novel inhibitor of monooxygenase reversed the activity of tetracyclines against tet(X3)/tet(X4)-positive bacteria. [Abstract]

2022 Apr;78:103943. PMID: 35306337
SLAS Discov

A Novel Flow Cytometric Assay to Identify Inhibitors of RBPJ-DNA Interactions. [Abstract]

2020 Sep;25(8):895-905. PMID: 32567455

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ying Xi, et al. Inhibition of epithelial-to-mesenchymal transition and pulmonary fibrosis by methacycline. Am J Respir Cell Mol Biol. 2014 Jan;50(1):51-60. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

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Methacycline

2 Cited Publications

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Publications (2)
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Methacycline

Publications Citing Use of MedChemExpress (MCE) Methacycline

All Antibiotic Isoforms

Biological Activity

Chemical Information

Publications (2)

순도&문서

References

Calculators

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Methacycline Related Classifications

HY-W587701 Related Classifications